Requirements & Curriculum Overview

Admissions Requirements

Applicants are expected 1) to have a strong foundation in the basic sciences, such as biology, chemistry and mathematics, and 2) to have training in computing/informatics, including significant computer programming experience. The Graduate Record Examination (GRE) General Test is required, and the GRE Subject Test in cell & molecular biology, biology, biochemistry, chemistry, computer science, or other relevant discipline is recommended. Alternatively, the Medical College Admission Test (MCAT) may be substituted for the GRE tests. Applicants for whom English is not their native language are required to submit results from the Test of English as a Foreign Language (TOEFL).

Requirements for the PhD degree

This section outlines the current CBB curriculum, and other requirements for the PhD degree. Because of the interdisciplinary nature of the field, we anticipate that the students will be extremely heterogeneous in their background and training. As a result, a welcoming/advisory committee will help students individually tailor the curriculum to their background and interests. The emphasis will be on gaining competency in three broad “core areas”:

  • computational biology and bioinformatics
  • biological sciences
  • informatics (including computer science, statistics, and applied mathematics)

Completion of the curriculum will typically take 4 semesters, depending in part on the prior training of the student. Since students may have very different prior training in biology and computing, the courses taken may vary considerably. In addition, students will spend a significant amount of time during this period doing intensive research rotations in faculty laboratories and attending relevant lectures and seminars.

Specifically, we expect that all students will:

  • take at least ten (10) courses as follows:
    • three (3) required graduate courses in computational biology and bioinformatics,
    • two (2) graduate courses in the biological sciences,
    • two (2) graduate courses in areas of informatics,
    • two (2) additional courses in any of the three core areas (which may be undergraduate courses taken to satisfy areas of minimum expected competency, as described below),
    • one (1) year-long graduate course that consists of three lab rotations taken over the fall and spring semesters of the first year, (graded as pass or fail),
    • any additional courses required to satisfy areas of minimum expected competency,
  • take a half-semester graduate seminar on research ethics in the 1st and 4th years, (graded as credit or non-credit)
  • participate in the CBB seminar series,
  • serve as a teaching assistant in two semester courses.

Students will typically take 2-3 courses each semester and 3 research rotations during the first year. Students are expected to find a dissertation advisor (or co-advisors) by the end of the first year. In the summer after the first year, students will start working in the laboratory of their chosen PhD supervisor. Students must pass a qualifying examination normally given at the end of the second year or the beginning of the third year. There is no language requirement.

In addition to the curriculum outlined above, the program has also defined an initial set of guidelines for minimum expected competency in biology, computer science, statistics, and mathematics. Some students may have satisfied all of these areas prior to entering our program. Other students may need to take undergraduate or graduate courses at Yale to satisfy one or more of these specific areas. These guidelines are in evolution and may be refined over time as we get more experience with the program.

MS Degree (en route to PhD)

A Master’s degree may be obtained by a CBB PhD student who is en route to obtaining a PhD degree or who leaves Yale prior to receiving a PhD degree. Requirements include: 1) completion of two years (four semesters) of study, 2) completion of required coursework (ten courses must be taken at Yale, including successful completion of three research rotations), and 3) satisfying the Graduate School requirement of two Honors grades.