Mohammed AlQuraishi, PhD (Columbia University)
“OpenFold: Lesson learned and insights gained from rebuilding and retraining AlphaFold”
Background
Mohammed AlQuraishi is an Assistant Professor in the Department of Systems Biology and a member of Columbia’s Program for Mathematical Genomics, where he works at the intersection of machine learning, biophysics, and systems biology. The AlQuraishi Lab focuses on two biological perspectives: the molecular and systems levels. On the molecular side, the lab develops machine learning models for predicting protein structure and function, protein-ligand interactions, and learned representations of proteins and proteomes. On the systems side, the lab applies these models in a proteome-wide fashion to investigate the organization, combinatorial logic, and computational paradigms of signal transduction networks, how these networks vary in human populations, and how they are dysregulated in human diseases, particularly cancer. Dr. AlQuraishi holds undergraduate degrees in Biology, Computer Science, and Mathematics. He earned an M.S. in Statistics and a Ph.D. in Genetics from Stanford University and was a Fellow in Systems Biology at Harvard Medical School prior to joining the Columbia Faculty.